Tuesday, November 10, 2009

ExPASy Proteomics Server

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Bioinformatics:Proteomics:ExPASy Proteomics Server:

Introduction:

Expasy Proteomics Server is a huge database which contains a variety of databases and a lot of tools and softwares used in molecular biology for analysing proteines.

The Expasy database contains a lot of ressources including:

1- Databases (SWISS-PROT, Prosite, ViralZone...etc ).
2- Tools and softwares to analyse proteines (Similarity searches, Post-translational modifications, Predicting proteines structures).

The databases included in the Expasy Proteomics Server are:

1- SWISS-PROT knowledgebase: a curated protein sequence database that provides high quality annotations (such as the description of the function of a protein, its domain structure, post-translational modifications and variants), a minimal level of redundancy and a high level of integration with other databases.
2- TrEMBL: contains computer-annotated entries for all sequences not yet integrated in SWISS-PROT. SWISS-PROT and TrEMBL are maintained collaboratively by the SIB and the European Bioinformatics Institute (EBI).
3- PROSITE: a database of protein domains and families. PROSITE contains biologically significant sites, patterns and profiles that help to reliably identify to which known protein family a new sequence belongs.
4- SWISS-MODEL Repository: a database of automatically generated structural protein models

And a lot of other Databases.

The Softwares includes in it are:

They have a huge amount of softwares, we will talk about some of them:

1- Softwares of Protein identification and characterization (Aldente, PepMAPPER...etc).
2- Prediction or characterization tools (ProtParam, PeptideMass...etc).
3- DNA to Protein softwares (Translation...etc).
4- Similarity searches (Blast).
5- Pattern and profile searches (InterPro Scan, PROSITE Scan).
6- Post-translational modification prediction (LipoP, Predotar).
7- Primary, Secondary, Tertiary structure analysis and Prediction.
8- Molecular modeling and visualization tools.

U know if i go on i'll not complete this list forever!!!so i'll stop here.

To access the EXPASY Proteomics Server click HERE
Or search in google for the term EXPASY and click the first entry.

Any questions, u're welcome

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