Bioinformatics: Proteomics

Bioinformatics: Proteomics

The word Proteome has came from the combination of the "protein" & "genome".

Proteomics is the study of proteines especially their structure and function and its the second step after genomics.

We all know that proteines are the molecules of life "as they say" because they are the acting molecules in every living organism, so by the study of Genomics and genes, we don't have every thing because:

1- Not all the genome codes for proteines (non coding regions "introns & exons").
2- The proteines will have post-translational modifications after they were translated (phosphorylation...etc).

The study of proteomics is more complicated than genomics because we're studying a variable thing that differs from cell to cell and from time to time.

By studying proteines we will discover:
1- Active sites that interacts with other molecules
2- Functions of these proteines.
3- Their location (transmembrane, outside or inside the cell)...etc.

Proteomics has solved a lot of problems and mysteries of many scinces like the case of the Alzheimer's disease in medecine, heart desease...etc

The main source of proteine sequences and information is the huge swissprot database, thanks to them the proteine analysis now is a peace of cake, you ca, find the data base here SWISSPROT