Bioinformatics:SWISSPROT & TrEMBL

Bioinformatics:SWISSPROT & TrEMBL Database

Swiss-Prot is a protein knowledgebase established in 1986 and maintained collaboratively by the Swiss Institute of Bioformatics (SIB) and the European Bioinformatics Institute (EBI).

The SwissProt Database provides a high level of annotation (a detailed file for each entry) that is mantained by expert biologists in the field and a high level of interaction with other Databases with a low level of redundancy.

The documentation is very easy for every one even with beginners in the field.

The TrEMBL protein sequence database was created in 1996 as a complement to Swiss-Prot in response to the need to make new sequences available as quickly as possible.

TrEMBL (Translation of EMBL nucleotide sequence database) initially consisted of computer annotated entries derived from the translation of all coding sequences (CDS) in the DDBJ/EMBL-Bank/GenBank nucleotide sequence database, except for those already included in Swiss-Prot. It now additionally contains protein sequences that are extracted from the literature or submitted to Swiss-Prot.

Now the SwissProt & TrEMBL Databases are playing a major role in Bioinformatics field (Proteomics to be accurate).

For more informations about Protein Sequence Databases you can read this post HERE

To learn how to use SwissProt to search for a specific Protein (Detailed lesson with a video) you can see HERE

For more informations about ExPASy Proteomics Server you can read this post HERE

Any questions you are welcome.