Wednesday, January 13, 2010

Bioinformatics: Proteomics: Protein Primary structure

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Bioinformatics: Proteomics: Protein Primary structure

As you know in structural bioinformatics, analysing protein structure begins by analysing its primary structure then secondary structure, then tertiary structure.

Primary structure doesn't give us informations about protein interaction with each other as secondary and tertiary structure do, but it gives you informations about segments in your protein that display a special composition, so with these informations we can retrieve protein properties like:

1- Hydrophobic regions: generally found anchored into the membrane.

2- Hydrophylic regions: we find them outside, so they form the protein surface.

3- coiled-coil regions: that indicate the protein-protein interaction potential.

Any comments you're welcome.

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